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01/07/2007

Oleander Soup- Cancer natural treatment

An Amazing Discovery in Turkey

By Tony M. Isaacs
Author of Cancer’s Natural Enemy



My own search for a possible cancer cure began in late 2004 when I found out that my cousin, lifelong friend and running buddy, Jeff Johnson, had been diagnosed as having stage-three melanoma. The cancer had appeared out of nowhere and so it was quite a shock to my cousin and everyone close to him. As luck would have it, I had spent a lot of time the previous four years or so working on my dream of someday posting a website aimed at helping aging baby boomers and others live longer, healthier and happier lives. Naturally, a lot of my research involved searching for ways to ward off and treat diseases and ills such as cancer, Alzheimer’s, heart disease, high blood pressure, kidney and liver disease, and so forth. When I found out about my cousin, I already had a head start on knowing where and how to look, and so I began to redouble my efforts and focus my research more on cancer. As a result of my research, I found a lot of very good information about fighting cancer and other diseases, boosting our immune systems and improving health in general - much of which you may find in my simple “How to Live a Long and Healthy Life” book. However, it was not my research that led me to finding out about the magical, miraculous oleander plant – it was a card game!

Yes, the way I first heard about the healing powers of oleander happened one evening when I was sitting down at a friendly card game and mentioned my cousin’s cancer. An acquaintance of mine whom I had known for a few years and who had worked for the American Medical Association at one time, looked across the table at me and, as serious as could be, said “I know a cure.” He then proceeded to tell me an amazing story of what he knew about oleander. Later, I found others who told me essentially the same basic story, although each person seemed to have a slightly different version. I fully expect that the story is headed toward becoming a modern day legend someday. Although the versions I heard have differed somewhat, the basic story line I believe to be essentially correct is as follows:

In the early 1960's a Turkish doctor by the name of Huseyin Ziya Ozel was searching for a cure for his pet dog’s cancer when he noticed that a large number of Turkish villagers referred to him came from high altitudes and he thought that perhaps there was more to the story than just the higher incidence of skin cancer associated with higher altitudes:

In many versions of the story, Doctor Ozel was reported to have observed Turkish villagers drinking an oleander remedy, which pretty much correlates with the description of Oleander Leaf on the American Cancer Society website, where it states that Doctor Ozel started his study of oleander because of folk traditions that suggested that an extract from oleander was active against leukemia. It should be noted that Doctor Ozel’s daughter Sumru disputes this version and states that Doctor Ozell “studied folkloric remedies and discovered that poultices made of crushed oleander leaves and flour were applied topically to wounds and produced amazingly fast healing of the wounds.” The author suspects that this version may have been put forward to put distance between what Ozel observed and what he later patented in order to protect the patent from challenges.

According to Ozel’s daughter, Doctor Ozel made an observation that the majority of cancer patients referring to him were coming from an altitude above 600 meters. He thought that there should be a correlation between the rate of cancer occurrence and some environmental influence.

Whatever the actual truth, Doctor Ozel obviously did observe Turkish villagers using oleander and did review that use as well as a number of environmental factors, and he proceeded to continue his research on oleander based on what he found.

Further research showed that Nerium Oleander was most abundant in lower altitudes and practically did not exist at high altitude. Satisfied that he may have determined the cause of the villager’s good health, Doctor Ozel became intrigued with the plant and began to prepare and work with various extracts of Oleander himself in 1966 while he was the head of the surgical department at Mugla State Hospital of Turkey.

Doctor Ozel first conducted animal studies to determine that the substance was non-toxic and, once he determined the toxicology and effects of Nerium Oleander Extract (or NOE), he conducted further experiments and developed his treatment in various forms until he eventually started tests on terminal human cases.

After initial success in treating human cancer patients with NOE, Doctor Ozel began to discussing his findings with other professionals in his field. He sought analysis of the extract from various Turkish laboratories to understand the empirical results. They were unable to characterize the extracted compounds. In hope of gaining assistance from the government or research organizations, he prepared a paper to present his first human cases at the Fourth Balkanic Medical Days Symposium held in Ankara on 20 September 1973.

The cases presented were all considered terminal cases when the patients came to Doctor Ozel. By law, he could not treat patients with an experimental drug, such as NOE, unless they had exhausted all other conventional treatment methods with no response or were diagnosed as advanced stage, terminal cases. At the symposium he was able to call the attention of the scientific community to NOE and how the extract had shown to be efficacious on cancer cases of different varieties. He was sure that his presentation would trigger serious and abundant research on NOE, and that it finally could be put into service for mankind.

The response from the scientific community was less than overwhelming. The skepticism centered mainly on the fact that the presentation contradicted what little literature there was on oleander species. Clearly the results presented could not be explained as an extension of prior art but Turkish scientists strongly denied the facts that Doctor Ozel had presented without any further research. To conclude, the medical community was reluctant to accept the results. Doctor Ozel was undaunted by the criticism and lack of support for the ideas presented. He continued his research and patients continued to seek treatment.

In 1974, he published additional case reports in the Turkish Medical Journal “Dirim”. Doctor Ozel resigned from his position as Chief Doctor at Mugla State Hospital that same year in order to be able to work on NOE and initiate research on the subject,

Doctor Ozel contacted various universities in Istanbul. Years passed and he realized that no serious scientific research could be performed in any of the local universities. In the meantime, his old patients referred new ones to him, and more cancer patients presented to him as word of the results of the treatment spread.

In 1985 he started to look for research facilities abroad. During 1986-1987 some tests performed in Europe proved the effect of NOE on the immune system as well as cancer tumors. The studies showed that it was at least six times as potent as the most active commercially available immune-stimulants (Schizophylan, Krestin and Lentinan, which were patented by the Japanese in the 1980s).

In 1988, a research team was formed at Munich University Pharmacology Institute to isolate the active components contained in the N.O. extract. Several polysaccharides were identified that might be responsible for some part of the immune activity. On 17-22 July 1990, the initial results were presented as a poster at the symposium of Biology and Chemistry of Active Natural Substances (BACANS) which was held in Bonn, Germany. The presentation was published in Planta Medica 1990-56:66. However, no single component of the extract was found to be the sole source of its benefits. Instead, the activity is induced by a complex mixture of components contained in the extract, acting synergistically to modulate the immune system. Since the early 1970’s, Doctor Ozel has been treating patients with advanced and inoperable cancer as well as a wide variety of other of illnesses. His results have been truly remarkable. In fact, so fantastic were the stories of his success that Doctor Ozel had to endure long periods of controversy from the Turkish medical establishment and there were those who tried to charge the good doctor with being a charlatan. Happily, the truth of his successes won out and such charges were dropped from consideration when his results were proven. Scores of patients rose up to defend the good doctor, testifying about how they had been cured when all other treatment options had failed.

The patented name of Doctor Ozel's oleander extract is Anvirzel™, whose trademark was once owned by Ozelle Pharmaceuticals, which was formed by Doctor Ozel’s son and other investors. Today, trademark rights are in dispute. Unfortunately, since Doctor Ozel had claimed that oleander was a cure for cancer, as opposed to a natural supplement, and since his extract was patented and given a trademark, the FDA now considers oleander as an unproven medicine which, because of the toxicity of the raw plant, must have it's safety and effectiveness proven before the FDA will allow it's use even as a herbal supplement, and so it is very difficult to obtain herbal supplements which contain oleander in the United States.

Today, the lengthy and costly three-phase FDA trial process for approval of Anvirzel™ or any other oleander extract, is far from over, although many people and millions of investor dollars are counting on it ultimately being approved. In 2000, Ozelle Pharmaceuticals had successful phase I FDA trials conducted on Anvirzel™, but subsequently ran into investor problems and had to reorganize. Although Ozelle continues to publish plans that it will soon begin phase II trials with Anvirzel™, such plans have not yet reached fruition and funding appears to continue to be a major problem for Ozelle.

In the interim, a competing company, Phoenix Biotech, also obtained a patent for Anvirzel™ in Honduras and has applied for a U.S. patent as well, and a clinic has been established in Honduras by the name of Salud Integral. For the past eight years, the clinic has successfully treated a number of patients, many of whom travel from the United States for initial diagnosis and treatment, as well as three-month supplies of Anvirzel™ for various cancers, hepatitis-C, psoriasis and other immune disorders.

Within just the past three years, a third competing company appeared by the name of Shimoda Atlantic Oncology Biosciences, and claimed to have developed its own oleander extract named Xenavex™ which it claimed was much stronger due to an ethanol extraction method. As it turned out, I and others exposed the company as a fraud that was created to cheat investors and the drug was actually a heart medication imported from Russia. Furthermore, although the imported Russian medicine does have slightly higher concentrations of oleandrin, the ethanol extraction method results in the loss of other compounds that researchers believe work together in a synergistic way to make oleander extract so powerful (over 500 trace compounds have been identified in an aqueous, or water, oleander extract, including vital long-chain polysaccharides that are lost in ethanol extraction methods because they precipitate out during the extraction process).

Sadly, I must report that it may be many years, if ever, before an oleander based medicine wins FDA approval. The simple fact is that it takes hundreds of millions of dollars to get a new drug successfully through all the FDA trials, and this pretty much bars competition to all but the very large pharmaceutical companies. Many feel that if the issue ever went to court, the patent itself would be hard to defend, since it is based on a common plant and a centuries-old folk remedy. Others feel that, because of the billions of dollars in profits at stake for the trillion-dollar world pharmaceutical industry and their myriad cancer treatments, no oleander medicine will ever be approved in the United States.

The best hope as of the time of this writing appears to be the development of an oleander based tablet by Phoenix Biotech which is reported to be have a much stronger concentration of oleandrin and the other cardiac glycosides while losing none of the other essential synergistic compounds. Only time will tell if a major pharmaceutical company with the requisite funds will pick up this new oleander product from Phoenix, shepherd it through FDA trials, and finally bring it to market.

A Brief History of the Oleander Plant

by Tony M. Isaacs
author of Cancer's Natural Enemy


In the Bible, the oleander plant is referred to as "the desert rose". Perhaps the name given this remarkable plant was no coincidence. Those of you who have read Dan Brown's entertaining combination of fact and fiction, "The Davinci Code", or who otherwise know a bit about pagan and early Christian religion will know that the rose is one of the most powerful of all religious symbols in pagan and early Christian religion and literature. It stands quite literally for nothing less than the feminine half of God, or the Goddess as that entity was called. It was also a symbol for very powerful healing.

an excerpt from "History of the Oleander in America... By Way of Galveston":

The first Oleanders came to subtropical Galveston in 1841. Joseph Osterman, a prominent merchant, brought them aboard his sailing ship from Jamaica to his wife and to his sister-in-law, Mrs. Isadore Dyer. Mrs. Dyer found them easy to cultivate and gave them to her friends and neighbors. The familiar double pink variety that she grew has been named for her. (Picture on right) Soon these new plants were growing throughout the city.

As early as 1846, note was taken of the yards in Galveston with oleanders and roses in full bloom and the contribution they made to the beauty of the city. Oleanders flourished in these early days of the city and were able to withstand the subtropical weather, the alkaline soil, and the salt spray. Therefore, it was logical for oleanders to be chosen as one of the predominent plants to be used in the replanting of the city following the destruction of the 1900 hurricane and grade raising that covered the existing vegetation with sand.

Concerned ladies of the city soon organized the Women's Health Protective Association (WHPA) with the mission to beautify the island and improve the health conditions of the city. They planted along Broadway, the entrance to the city, and on 25th Street, the path to the beach front, and in a few years, oleanders made a spectacular display of blooms for citizens and visitors. Although the name of the WHPA was changed to the Women's Civic League, planting continued for many years up and down city streets, in parks, in yards, around public buildings and schools and soon the whole city became a garden of oleanders. As early as 1908, an editorial in the Galveston Tribune observed that the oleander was emblematic of Galveston and that people came from all over to see them. In 1910, The Galveston Daily News also reported that Galveston was known throughout the world as "The Oleander City" and in 1916, an article named it one of the most beautiful cities in the South.

Through the pollination of the two original Galveston Oleanders, 'Mrs. Isadore Dyer' and 'Ed Barr', many hybrids have occured throughout the century. Many of these were distributed all over the United States and, today, are growing everywhere the climate is amicable. Today, corals, yellows, reds, pinks and whites in singles and double forms are found in the warmer climates of America.

(To read the complete article go to http://oleander.org/history.html. And, for a marvelously detailed article about the world history of the oleander plant, go to http://oleander.org/fromwhence.html)

Medicinal use of the oleander plant dates back at least 3500 years. Historical records show that the Mesopotamians in the 15th century BC believed in the healing properties of oleander. The Babylonians used a mixture of oleander and licorice to treat hangovers. Roman soldiers also regularly took an oleander extract for hangovers. Pliny, the Elder of ancient Greece, wrote about the appearance and properties of oleander. Arab physicians first used oleander as a cancer treatment in the 8th century AD.

Centuries later, in the 1633 edition of "The Herbal, or General History of Plants", the author John Gerard says of oleander: "This tree being outwardly applied, as Galen saith, hath a digesting faculty; but if it be inwardly taken it is deadly and poisonsome, not only to men, but also to most kinds of beasts. The flowers and leaves kill dogs, asses, mules, and very many of other four footed beasts: but if men drink them in wine they are a remedy against the bitings of Serpents, and the rather if Rue be added. The weaker sort of cattle, as sheep and goats, if they drink the water wherein the leaves have been steeped, are sure to die." which indicates knowledge that the raw plant is poisonous, but that extracts of the plant were used medicinally. And, an oleander extract much like oleander soup is most likely the magic healing potion that led to the witchcraft accusation against Rebecca, the beautiful Jewish woman from the Holy Land, in Sir Walter Scott's "Ivanhoe".

In recent centuries, oleander has continued to be used in folk remedies and in commercial preparations in the Middle East, Russia, China and the South American rain forest. Currently, a Brazilian manufacturer is making and distributing an amazing supplement called OPC Extract worldwide, and the patent holder in South Africa, Marc Swanepoel, is making the supplement as well and using it, along with doctors and caregivers, with remarkable success against HIV and cancer.

Thanks to a Texas attorney and perhaps a bit of help from others like your humble author, a growing number of people around the world are now able to make their own oleander remedy. In the concluding installments, we will take a look at how effectively oleander is being used against cancer and HIV in South Africa, where you can obtain the patented oleander medicine as well as oleander extracts such as the one used in South Africa, and how to make your own oleander extract for only pennies.


Oleander Soup

http://www.cancertutor.com/Cancer02/Oleander.html

Virtually every substance a person puts in their mouth is toxic if taken in high enough doses. Sugar is toxic if you eat too much of it. Processed salt is toxic if you eat too much of it. And so on.

One of the interesting things about cancer cells is that they are more fragile than normal cells to certain chemicals. Sugar is NOT one of these substances because cancer cells feed on sugar. Thus, there is absolutely no level of sugar that will be toxic to cancer cells, but not toxic to non-cancerous cells.

As another example, chemotherapy also does NOT fit into this category. Chemotherapy does not target cancer cells, meaning it does not kill cancer cells without doing severe damage to normal (i.e. non-cancerous) cells. It kills both kinds of cells.

However, it is well known that there exist natural substances in nature that are toxic to cancer cells, but harmless to normal cells. In fact, there are many natural substances that fit into this category. For example, purple grapes have more than a dozen such substances and may contain many more.

One of the goals of cancer researchers is to find substances that are toxic enough to kill cancer cells, but not so toxic that they kill non-cancerous cells.

But what about the idea of starting with a very toxic plant, even toxic to normal cells, but dilute it enough so that it is still toxic to cancer cells, but not toxic to normal cells? That is exactly what has been achieved.

The oleander plant well-known to be very toxic. When handling the plant it should be handled with gloves. There are many other safety warnings when dealing with the oleander plant. It is very toxic.

But one of the interesting things about the oleander plant is that if you dilute it exactly the right amount, it is still toxic enough to kill cancer cells, but with the proper dilution, it will not kill normal cells.

This level of dilution and toxicity is now well-known. This treatment can be safely be done at home!!

The history of the oleander soup can be traced to Turkey. As with so many other discoveries, a researcher found a group of people who had a vastly lower rate of disease than other groups of people in the same country. Upon investigation, a Dr. Huseyin Z. Ozel found out these people had been taking a folk remedy for their diseases. The remedy was a diluted form of the oleander plant.

Dr. Ozel actually applied for a patent for his discovery. In his patent application he mentions several case studies as well as one study which included 494 patients. Here is a quote from the patent application:


"Between January 1981 and December, 1985, 494 patients with inoperable, advanced malignant diseases were tested with NOI [injection of formula]. All malignancy had previously been diagnosed at various specialized medical institutions in Turkey and abroad. The malignancies of these patients had progressed to a state where they could no longer benefit from existing anti-tumor therapies. These 494 cases included examples of almost all varieties of malignancies and were found in various organs.
Patent Office Website
The patent application can be found by copying and pasting together the following very long URL:

http://patft.uspto.gov/netacgi/nph-Parser?...F&d=PALL&p=1&u=
/netahtml/srchnum.htm&r=1&f=G&l=50&s1=5,135,745.WKU.&OS=PN/5,135,745&RS=PN/5,135,745

The results of the study were very satisfactory to those involved.

It is Dr. Ozel who also first thought of the concept of an oleander soup that can be made at home. No doubt it was influenced by the people he studied in the small villages in Turkey.

Let me quote from an email I received from Tony Isaacs, the author of the book I will mention below:


"I have heard nothing but good reports from those who have been using oleander soup or the oleander extract available now at Takesun do Brasil. Cancers gone, cancers in remission, tumors shrinking, etc. And the reports out of South Africa, where the government has embraced the mixture of oleander plus agaricus blazei murrill, pau de arco and cat's claw extract combo (80% oleander) is that every single patient is doing well. HIV-AIDS halted and stabilized or even apparently reversed. And not one single report to date of a serious side effect or adverse reaction to oleander extract. It is a good feeling to be able to help someone."
Some time ago I followed a news group on oleander soup (actually the news group was about a drug under development). The comments I read from the news group make Tony's statement very believable to me.

For those who do not live in an area of the world where the oleander plant grows wild, I am sure they can obtain the seeds for the plant by searching the Internet. The bad thing about doing that is that most cancer patients don't want to wait for a plant to grow. Thus, it might be best to buy actual live plants over the Internet or perhaps at a flower shop, if they are available in your area. Tony may have some far better ideas and resources for obtaining the plant or the key parts of the plant.

The best source of information about actually making the oleander soup is a very inexpensive eBook. What is nice about eBooks is that because they are electronic they can be updated very easily, thus, you are always buying the most current information. Here is the key web site:
Cancer's Natural Enemy; http://www.rose-laurel.com/

One word of warning: Even though the dilution factor is now well established, BEFORE you even begin processing a real oleander plant, the section of the article or book you are depending on for instructions should be read SEVERAL times, while taking notes, to insure before you even start that you are going to do it right the first time!!

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